Systematic identification of cell size regulators in budding yeast

@inproceedings{Soifer2014SystematicIO,
  title={Systematic identification of cell size regulators in budding yeast},
  author={Ilya Soifer and Naama Barkai},
  booktitle={Molecular systems biology},
  year={2014}
}
Cell size is determined by a complex interplay between growth and division, involving multiple cellular pathways. To identify systematically processes affecting size control in G1 in budding yeast, we imaged and analyzed the cell cycle of millions of individual cells representing 591 mutants implicated in size control. Quantitative metric distinguished mutants affecting the mechanism of size control from the majority of mutants that have a perturbed size due to indirect effects modulating cell… CONTINUE READING
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