Systematic discovery of novel ciliary genes through functional genomics in the zebrafish

  title={Systematic discovery of novel ciliary genes through functional genomics in the zebrafish},
  author={Semil P. Choksi and D. Erri Babu and Doreen A H Lau and Xianwen Yu and Sudipto Kumar Roy},
Cilia are microtubule-based hair-like organelles that play many important roles in development and physiology, and are implicated in a rapidly expanding spectrum of human diseases, collectively termed ciliopathies. Primary ciliary dyskinesia (PCD), one of the most prevalent of ciliopathies, arises from abnormalities in the differentiation or motility of the motile cilia. Despite their biomedical importance, a methodical functional screen for ciliary genes has not been carried out in any… CONTINUE READING
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