Systematic determination of patterns of gene expression during Drosophila embryogenesis

  title={Systematic determination of patterns of gene expression during Drosophila embryogenesis},
  author={Pavel Tomançak and Amy Beaton and Richard Weiszmann and Elaine Kwan and ShengQiang Shu and Suzanna E. Lewis and Stephen Richards and Michael Ashburner and Volker Hartenstein and Susan E. Celniker and Gerald M. Rubin},
  journal={Genome Biology},
  pages={research0088.1 - 88.14}
Cell-fate specification and tissue differentiation during development are largely achieved by the regulation of gene transcription. As a first step to creating a comprehensive atlas of gene-expression patterns during Drosophila embryogenesis, we examined 2,179 genes by in situ hybridization to fixed Drosophila embryos. Of the genes assayed, 63.7% displayed dynamic expression patterns that were documented with 25,690 digital photomicrographs of individual embryos. The photomicrographs were… CONTINUE READING
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