Systematic characterization of flavonoids from Siraitia grosvenorii leaf extract using an integrated strategy of high-speed counter-current chromatography combined with ultra-performance liquid chromatography electrospray ionization quadrupole time-of-flight mass spectrometry.

@article{Lu2019SystematicCO,
  title={Systematic characterization of flavonoids from Siraitia grosvenorii leaf extract using an integrated strategy of high-speed counter-current chromatography combined with ultra-performance liquid chromatography electrospray ionization quadrupole time-of-flight mass spectrometry.},
  author={Ying Lu and Shihao Zhu and Yingjie He and Chang-ming Mo and Changqiao Wu and Ruiying Zhang and Xue-Fang Zheng and Qi Tang},
  journal={Journal of separation science},
  year={2019}
}
In this paper, the chemical constituents of the Siraitia grosvenorii leaf extract were studied. Firstly, High-speed counter-current chromatography was applied to the one-step separation of four compounds from S. grosvenorii leaf extract with the solvent system composed of 0.01% acetic acid water/n-butanol/n-hexane/methanol (5:3:1:1, v/v/v/v). In this work, 270 mg of crude sample yielded four compounds, a new kaempferol O-glycoside derivative, kaempferol 3-O-α-L-[4-O-(4-carboxy-3-hydroxy-3… 
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