Systematic antibody generation and validation via tissue microarray technology leading to identification of a novel protein prognostic panel in breast cancer

@inproceedings{OLeary2012SystematicAG,
  title={Systematic antibody generation and validation via tissue microarray technology leading to identification of a novel protein prognostic panel in breast cancer},
  author={Patrick C O´Leary and Sarah A Penny and Roisin T. Dolan and Catherine M. Kelly and Stephen F. Madden and Elton Rexhepaj and Donal J Brennan and Amanda H McCann and Fredrik Pont{\'e}n and Mathias Uhl{\'e}n and Radoslaw Zagozdzon and Michael J. Duffy and Malcolm R. Kell and Karin Jirstr{\"o}m and William M. Gallagher},
  booktitle={BMC Cancer},
  year={2012}
}
Although omic-based discovery approaches can provide powerful tools for biomarker identification, several reservations have been raised regarding the clinical applicability of gene expression studies, such as their prohibitive cost. However, the limited availability of antibodies is a key barrier to the development of a lower cost alternative, namely a discrete collection of immunohistochemistry (IHC)-based biomarkers. The aim of this study was to use a systematic approach to generate and… CONTINUE READING
Highly Cited
This paper has 152 citations. REVIEW CITATIONS
Recent Discussions
This paper has been referenced on Twitter 4 times over the past 90 days. VIEW TWEETS
21 Citations
62 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 21 extracted citations

153 Citations

05010020142015201620172018
Citations per Year
Semantic Scholar estimates that this publication has 153 citations based on the available data.

See our FAQ for additional information.

References

Publications referenced by this paper.
Showing 1-10 of 62 references

Similar Papers

Loading similar papers…