Systematic analysis of the transcriptional switch inducing migration of border cells.

@article{Borghese2006SystematicAO,
  title={Systematic analysis of the transcriptional switch inducing migration of border cells.},
  author={Lodovica Borghese and G. Fletcher and Juliette Mathieu and Ann Kathleen Atzberger and William C. Eades and Ross L. Cagan and Pernille R\orth},
  journal={Developmental cell},
  year={2006},
  volume={10 4},
  pages={497-508}
}
Cell migration within a natural context is tightly controlled, often by specific transcription factors. However, the switch from stationary to migratory behavior is poorly understood. Border cells perform a spatially and temporally controlled invasive migration during Drosophila oogenesis. Slbo, a C/EBP family transcriptional activator, is required for them to become migratory. We purified wild-type and slbo mutant border cells as well as nonmigratory follicle cells and performed comparative… CONTINUE READING