Systematic analysis of the lysine acetylome in Vibrio parahemolyticus.

@article{Pan2014SystematicAO,
  title={Systematic analysis of the lysine acetylome in Vibrio parahemolyticus.},
  author={Jianyi Pan and Zhicang Ye and Zhongyi Cheng and Xiaojun Peng and Liangyou Wen and Fukun Zhao},
  journal={Journal of proteome research},
  year={2014},
  volume={13 7},
  pages={3294-302}
}
Lysine acetylation of proteins is a major post-translational modification that plays an important regulatory role in almost every aspect of cells, both eukaryotes and prokaryotes. Vibrio parahemolyticus, a model marine bacterium, is a worldwide cause of bacterial seafood-borne illness. Here, we conducted the first lysine acetylome in this bacterium through a combination of highly sensitive immune-affinity purification and high-resolution LC-MS/MS. Overall, we identified 1413 lysine acetylation… CONTINUE READING
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