Systematic analysis of human lysine acetylation proteins and accurate prediction of human lysine acetylation through bi-relative adapted binomial score Bayes feature representation.

@article{Shao2012SystematicAO,
  title={Systematic analysis of human lysine acetylation proteins and accurate prediction of human lysine acetylation through bi-relative adapted binomial score Bayes feature representation.},
  author={Jianlin Shao and Dong Xu and Lan-Dian Hu and Y. I. Kwan and Yifei Wang and Xiangyin Kong and Sai-ming Ngai},
  journal={Molecular bioSystems},
  year={2012},
  volume={8 11},
  pages={2964-73}
}
Lysine acetylation is a reversible post-translational modification (PTM) which has been linked to many biological and pathological implications. Hence, localization of lysine acetylation is essential for deciphering the mechanism of such implications. Whereas many acetylated lysines in human proteins have been localized through experimental approaches in wet lab, it still fails to reach completion. In the present study, we proposed a novel feature extraction approach, bi-relative adapted… CONTINUE READING

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