Systematic analysis of gene expression alterations and clinical outcomes of adenylate cyclase-associated protein in cancer

@inproceedings{Xie2017SystematicAO,
  title={Systematic analysis of gene expression alterations and clinical outcomes of adenylate cyclase-associated protein in cancer},
  author={Shuanshuan Xie and Changxing Shen and Min Tan and Ming Hui Li and Xiaolian Song and Changhui Wang},
  booktitle={Oncotarget},
  year={2017}
}
Adenylate Cyclase-associated protein (CAP) is an evolutionarily conserved protein that regulates actin dynamics. Our previous study indicates that CAP1 is overexpressed in NSCLC tissues and correlated with poor clinical outcomes, but CAP1 in HeLa cells actually inhibited migration and invasion, the role of CAP was discrepancy in different cancer types. The present study aims to determine whether CAP can serve as a prognostic marker in human cancers. The CAP expression was assessed using… CONTINUE READING
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