Systematic Review and Pooled Estimates for the Diagnostic Accuracy of Serological Markers for Intestinal Ischemia

@article{Evennett2009SystematicRA,
  title={Systematic Review and Pooled Estimates for the Diagnostic Accuracy of Serological Markers for Intestinal Ischemia},
  author={Nicholas J. Evennett and Maxim S. Petrov and Anubhav Mittal and John Albert Windsor},
  journal={World Journal of Surgery},
  year={2009},
  volume={33},
  pages={1374-1383}
}
BackgroundIntestinal ischemia is a potentially catastrophic abdominal emergency that presents a significant diagnostic challenge in the critical care setting. We performed a systematic review of the literature to define the diagnostic accuracy of serological markers of intestinal ischemia.MethodsObservational studies on the performance of markers of intestinal ischemia were identified within the MEDLINE and EMBASE electronic databases. All studies from which it was possible to derive true… 
Diagnostic accuracy of novel serological biomarkers to detect acute mesenteric ischemia: a systematic review and meta-analysis
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It is considered that PCT can be used in daily practice as a tool for diagnosing intestinal ischemia, and the preclinical and clinical data suggest that it does not need to be placed in the basket of diagnostic tools for this condition.
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TLDR
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Biochemical markers of acute intestinal ischemia: possibilities and limitations.
TLDR
Among the various tests, D-lactate, IMA and I-FABP are perhaps the most promising, since they are characterized by optimal sensitivity and relatively good specificity, early kinetics, and can be measured with assays suited for a rapid diagnosis.
A Novel Scoring System for Diagnosing Acute Mesenteric Ischemia in the Emergency Ward
TLDR
A scoring system based on easily available parameters could be used as a useful tool for differentiating AMI from other acute abdomen in the emergency ward and validating the results with large sample remain needed.
Current status on plasma biomarkers for acute mesenteric ischemia
TLDR
None of the proposed plasma-derived tests for acute mesenteric ischemia has as yet entered routine clinical practice, and the encouraging preliminary result of cobalt-albumin and urinary FABP as an accurate marker needs to be addressed in other study populations.
Diagnostic accuracy of multidetector CT in acute mesenteric ischemia: systematic review and meta-analysis.
TLDR
On the basis of a thorough clinical examination, contrast-enhanced multidetector CT allows the diagnosis of primary AMI with high sensitivity and specificity and may be used as the first-line imaging method.
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