Systematic Identification of Novel, Essential Host Genes Affecting Bromovirus RNA Replication

@inproceedings{Gancarz2011SystematicIO,
  title={Systematic Identification of Novel, Essential Host Genes Affecting Bromovirus RNA Replication},
  author={Brandi Gancarz and Linhui Hao and Qiuling He and Michael A. Newton and Paul Ahlquist},
  booktitle={PloS one},
  year={2011}
}
Positive-strand RNA virus replication involves viral proteins and cellular proteins at nearly every replication step. Brome mosaic virus (BMV) is a well-established model for dissecting virus-host interactions and is one of very few viruses whose RNA replication, gene expression and encapsidation have been reproduced in the yeast Saccharomyces cerevisiae. Previously, our laboratory identified ∼100 non-essential host genes whose loss inhibited or enhanced BMV replication at least 3-fold. However… CONTINUE READING
19 Citations
66 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 19 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 66 references

Inhibition of the Ubiquitin-Proteasome System Affects Influenza A Virus Infection at a Postfusion Step

  • I Widjaja, E de Vries, DM Tscherne, A Garcia-Sastre, PJM Rottier
  • J Virol
  • 2010
1 Excerpt

Similar Papers

Loading similar papers…