Systematic Evaluation of Three microRNA Profiling Platforms: Microarray, Beads Array, and Quantitative Real-Time PCR Array

@inproceedings{Wang2011SystematicEO,
  title={Systematic Evaluation of Three microRNA Profiling Platforms: Microarray, Beads Array, and Quantitative Real-Time PCR Array},
  author={Bin Wang and Paul Howel and Skjalg Bruheim and Jingfang Ju and Laurie B. Owen and Oystein Fodstad and Yaguang Xi},
  booktitle={PloS one},
  year={2011}
}
BACKGROUND A number of gene-profiling methodologies have been applied to microRNA research. The diversity of the platforms and analytical methods makes the comparison and integration of cross-platform microRNA profiling data challenging. In this study, we systematically analyze three representative microRNA profiling platforms: Locked Nucleic Acid (LNA) microarray, beads array, and TaqMan quantitative real-time PCR Low Density Array (TLDA). METHODOLOGY/PRINCIPAL FINDINGS The microRNA profiles… CONTINUE READING