Systematic Analysis of Circadian Genes in a Population-Based Sample Reveals Association of TIMELESS with Depression and Sleep Disturbance

@inproceedings{Utge2010SystematicAO,
  title={Systematic Analysis of Circadian Genes in a Population-Based Sample Reveals Association of TIMELESS with Depression and Sleep Disturbance},
  author={Siddheshwar J. Utge and Pia Soronen and Anu Loukola and Erkki Kronholm and Hanna Maria Ollila and Sami P. Pirkola and Tarja Porkka-Heiskanen and Timo Partonen and Tiina Paunio},
  booktitle={PloS one},
  year={2010}
}
Disturbances in the circadian pacemaker system are commonly found in individuals with depression and sleep-related problems. We hypothesized that some of the canonical circadian clock genes would be associated with depression accompanied by signs of disturbed sleep, early morning awakening, or daytime fatigue. We tested this hypothesis in a population-based sample of the Health 2000 dataset from Finland, including 384 depressed individuals and 1270 controls, all with detailed information on… CONTINUE READING
29 Citations
93 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 29 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 93 references

A simple model for circadian timing by mammals

  • FR Cardoso, OCFA de, D Silva, CM Cortez
  • Braz J Med Biol Res
  • 2009
1 Excerpt

Similar Papers

Loading similar papers…