System in Mouse and Rat Heart Connexin 45 Expression Is Preferentially Associated With the Ventricular Conduction

@inproceedings{Coppen1998SystemIM,
  title={System in Mouse and Rat Heart Connexin 45 Expression Is Preferentially Associated With the Ventricular Conduction},
  author={Steven R. Coppen and E. Dupont and Stephen Rothery and Nicholas J. Severs},
  year={1998}
}
Cardiac myocytes are electrically coupled by gap junctions, clusters of low-resistance intercellular channels composed of connexins. Variations in the quantities and spatial distribution of different connexin types have been implicated in regional differentiation of electrophysiological properties in the heart. Although independent studies have demonstrated that connexin43 is abundant in working ventricular myocardium and that connexin40 is preferentially expressed in the atrioventricular… CONTINUE READING

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Gap junctions and connexins in the cardiovascular system

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