System-Level Biochip for Impedance Sensing and Programmable Manipulation of Bladder Cancer Cells

  title={System-Level Biochip for Impedance Sensing and Programmable Manipulation of Bladder Cancer Cells},
  author={Cheng-Hsin Chuang and Yao-Wei Huang and Yao-Tung Wu},
This paper develops a dielectrophoretic (DEP) chip with multi-layer electrodes and a micro-cavity array for programmable manipulations of cells and impedance measurement. The DEP chip consists of an ITO top electrode, flow chamber, middle electrode on an SU-8 surface, micro-cavity arrays of SU-8 and distributed electrodes at the bottom of the micro-cavity. Impedance sensing of single cells could be performed as follows: firstly, cells were trapped in a micro-cavity array by negative DEP force… CONTINUE READING
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