Synthetically prepared Amadori‐glycated phosphatidylethanolamine can trigger lipid peroxidation via free radical reactions

@article{Oak2000SyntheticallyPA,
  title={Synthetically prepared Amadori‐glycated phosphatidylethanolamine can trigger lipid peroxidation via free radical reactions},
  author={J. Oak and K. Nakagawa and T. Miyazawa},
  journal={FEBS Letters},
  year={2000},
  volume={481}
}
  • J. Oak, K. Nakagawa, T. Miyazawa
  • Published 2000
  • Chemistry, Medicine
  • FEBS Letters
  • This study for the first time confirmed the peroxidative role of the Amadori product derived from the glycation of phosphatidylethanolamine (PE), namely Amadori–PE. The product was synthesized from the reaction of dioleoyl PE with D‐glucose, and then purified by a solid‐phase extraction procedure, which was a key step in the next HPLC technique for the isolation of essentially pure Amadori–PE. When the synthetically prepared Amadori–PE was incubated with linoleic acid in the presence of Fe3+ in… CONTINUE READING
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