Synthetically accessible, high-affinity phosphate anion receptors.

  title={Synthetically accessible, high-affinity phosphate anion receptors.},
  author={Hubertus Bart F M Nelissen and David K Smith},
  journal={Chemical communications},
We report synthetically accessible receptors with protonated amines attached to a conformationally constrained backbone including amide units, and demonstrate that these receptors have high affinities (log K > 5) for phosphate anions in aqueous media at pH 7 in the presence of high concentrations of competitive chloride anions (ca. 100-fold excess).