Synthetic viruslike particles and hybrid constructs based on lipopeptide self-assembly.

@article{Perriman2010SyntheticVP,
  title={Synthetic viruslike particles and hybrid constructs based on lipopeptide self-assembly.},
  author={Adam W. Perriman and David S Williams and Andrew J Jackson and Isabelle Grillo and Jimy M Koomullil and Arin Ghasparian and John Alan Robinson and Stephen Mann},
  journal={Small},
  year={2010},
  volume={6 11},
  pages={1191-6}
}
The spontaneous self-assembly of biological molecules to form viruslike particles (VLPs) represents a key area of research in biotechnology and pharmacology. Use of VLP-based vaccines is expected to contribute significantly to new advances in health care; for example, the human papilloma virus (HPV) and hepatitis B virus vaccines were recently approved by the Food and Drug Administration (FDA). VLPs are most commonly derived from recombinant proteins that assemble to form capsids devoid of… CONTINUE READING