Synthetic studies directed toward the assembly of the C-glycoside fragment of the telomerase inhibitor D8646-2-6.

@article{Kanai2003SyntheticSD,
  title={Synthetic studies directed toward the assembly of the C-glycoside fragment of the telomerase inhibitor D8646-2-6.},
  author={Akira Kanai and T. Kamino and K. Kuramochi and Susumu Kobayashi},
  journal={Organic letters},
  year={2003},
  volume={5 16},
  pages={
          2837-9
        }
}
[reaction: see text] Construction and characterization of the C-glycosidic moiety of telomerase inhibitor D8646-2-6 (1) are described. This is the first example of the C-glycosylation using electron-poor aromatics, 4-hydroxypyrone, as a glycosyl acceptor. The glycosylation reaction and base-promoted isomerization affords desired beta-C-glycoside in a 61% overall yield. 

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Recent Advances in the Chemical Synthesis of C-Glycosides.
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