Synthetic riboswitches - A tool comes of age.

@article{Groher2014SyntheticR,
  title={Synthetic riboswitches - A tool comes of age.},
  author={Florian Groher and Beatrix Suess},
  journal={Biochimica et biophysica acta},
  year={2014},
  volume={1839 10},
  pages={964-973}
}
Within the last decade, it has become obvious that RNA plays an important role in regulating gene expression. This has led to a plethora of approaches aiming at exploiting the outstanding chemical properties of RNA to develop synthetic RNA regulators for conditional gene expression systems. Consequently, many different regulators have been developed to act on various stages of gene expression. They can be engineered to respond to almost any ligand of choice and are, therefore, of great interest… CONTINUE READING
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