Synthetic retinoids in dermatology.

  title={Synthetic retinoids in dermatology.},
  author={E H Heller and N J Shiffman},
  journal={Canadian Medical Association journal},
  volume={132 10},
The potential of vitamin A, or retinol, in the treatment of a variety of skin diseases has long been recognized, but because of serious toxic effects this substance generally could not be used. The recent development and marketing of two relatively non-toxic synthetic analogues, which are known as retinoids, has made it possible to treat some of the diseases that are resistant to standard forms of therapy. Isotretinoin is very effective in cystic and conglobate acne, while etretinate is… CONTINUE READING