Synthetic pulmonary surfactant preparations: new developments and future trends.

@article{Mingarro2008SyntheticPS,
  title={Synthetic pulmonary surfactant preparations: new developments and future trends.},
  author={Ismael Mingarro and Dunja Lukovic and Marçal Vilar and Jes{\'u}s P{\'e}rez-Gil},
  journal={Current medicinal chemistry},
  year={2008},
  volume={15 4},
  pages={
          393-403
        }
}
Pulmonary surfactant is a lipid-protein complex that coats the interior of the alveoli and enables the lungs to function properly. Upon its synthesis, lung surfactant adsorbs at the interface between the air and the hypophase, a capillary aqueous layer covering the alveoli. By lowering and modulating surface tension during breathing, lung surfactant reduces respiratory work of expansion, and stabilises alveoli against collapse during expiration. Pulmonary surfactant deficiency, or dysfunction… CONTINUE READING