Synthetic nanoparticles camouflaged with biomimetic erythrocyte membranes for reduced reticuloendothelial system uptake.

@article{Rao2016SyntheticNC,
  title={Synthetic nanoparticles camouflaged with biomimetic erythrocyte membranes for reduced reticuloendothelial system uptake.},
  author={Lang Rao and Jun-hua Xu and Bo Cai and Huiqin Liu and Ming Li and Yan Jia and Liang Xiao and Shi-Shang Guo and Wei Liu and X Zhao},
  journal={Nanotechnology},
  year={2016},
  volume={27 8},
  pages={085106}
}
Suppression of the reticuloendothelial system (RES) uptake is one of the most challenging tasks in nanomedicine. Coating stratagems using polymers, such as poly(ethylene glycol) (PEG), have led to great success in this respect. Nevertheless, recent observations of immunological response toward these synthetic polymers have triggered a search for better alternatives. In this work, natural red blood cell (RBC) membranes are camouflaged on the surface of Fe3O4 nanoparticles for reducing the RES… CONTINUE READING

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