Synthetic innate defense regulator peptide combination using CpG ODN as a novel adjuvant induces long‑lasting and balanced immune responses.

@article{Yu2016SyntheticID,
  title={Synthetic innate defense regulator peptide combination using CpG ODN as a novel adjuvant induces long‑lasting and balanced immune responses.},
  author={Chao-Heng Yu and Zi-chao Luo and Meng Li and Lian Lu and Zhan Li and Xiao-Zhe Wu and Ying-Zi Fan and Hai-long Zhang and B Zhou and Yang Wan and Ke Men and Yao-Mei Tian and Shuang Xiu Chen and Feng-Jiao Yuan and Rong Xiang and Li Yang},
  journal={Molecular medicine reports},
  year={2016},
  volume={13 1},
  pages={915-24}
}
Vaccines are critical tools for the prevention and treatment of several diseases. Adjuvants have been traditionally used to enhance immunity to vaccines and experimental antigens. In the present study, the adjuvant combination of CpG oligodeoxynucleotides (CpG ODN) and the innate defense regulator (IDR) peptide, IDR‑HH2, was evaluated for its ability to… CONTINUE READING