Synthetic fluorescent probes for studying copper in biological systems.

@article{Cotruvo2015SyntheticFP,
  title={Synthetic fluorescent probes for studying copper in biological systems.},
  author={Joseph A. Cotruvo and Allegra T. Aron and Karla M. Ramos-Torres and Christopher J Chang},
  journal={Chemical Society reviews},
  year={2015},
  volume={44 13},
  pages={4400-14}
}
The potent redox activity of copper is required for sustaining life. Mismanagement of its cellular pools, however, can result in oxidative stress and damage connected to aging, neurodegenerative diseases, and metabolic disorders. Therefore, copper homeostasis is tightly regulated by cells and tissues. Whereas copper and other transition metal ions are… CONTINUE READING