Synthetic disialylgalactose immunoadsorbents deplete anti-GQ1b antibodies from autoimmune neuropathy sera.

@article{Willison2004SyntheticDI,
  title={Synthetic disialylgalactose immunoadsorbents deplete anti-GQ1b antibodies from autoimmune neuropathy sera.},
  author={Hugh John Willison and Kate H Townson and Jean Veitch and Judith Boffey and Neil S. Isaacs and Soren M Andersen and Ping Zhang and Chang-Chun Ling and David R Bundle},
  journal={Brain : a journal of neurology},
  year={2004},
  volume={127 Pt 3},
  pages={680-91}
}
Acute and chronic autoimmune neuropathies, including Guillain-Barré syndromes (GBS) are often characterized by the presence of autoantibodies that react with neural gangliosides. Evidence from human and animal studies indicates that anti-ganglioside antibodies play a primary neuropathogenic role, and their rapid elimination from the circulation through specific immunoadsorption therapy thus has the potential to ameliorate the course of the disease. Here we have tested this therapeutic principle… CONTINUE READING

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