Synthetic conversion of a graded receptor signal into a tunable, reversible switch

Abstract

The ability to engineer an all-or-none cellular response to a given signaling ligand is important in applications ranging from biosensing to tissue engineering. However, synthetic gene network 'switches' have been limited in their applicability and tunability due to their reliance on specific components to function. Here, we present a strategy for… (More)
DOI: 10.1038/msb.2011.13

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Cite this paper

@inproceedings{Palani2011SyntheticCO, title={Synthetic conversion of a graded receptor signal into a tunable, reversible switch}, author={Santhosh Palani and Casim A. Sarkar}, booktitle={Molecular systems biology}, year={2011} }