Synthetic chalcones as potential anti-inflammatory and cancer chemopreventive agents.

@article{Won2005SyntheticCA,
  title={Synthetic chalcones as potential anti-inflammatory and cancer chemopreventive agents.},
  author={Shen J. Won and Cheng-Tsung Liu and Lo T. Tsao and Jing-Ru Weng and Horng Huey Ko and Jih P. Wang and Chun-Nan Lin},
  journal={European journal of medicinal chemistry},
  year={2005},
  volume={40 1},
  pages={
          103-12
        }
}
In an effort to develop potent anti-inflammatory and cancer chemopreventive agents, a series of chalcones were prepared by Claisen-Schmidt condensation of appropriate acetophenones with suitable aromatic aldehyde or prepared with appropriate dihydrochalcone reacted with appropriate alkyl bromide or prepared in one-pot procedure involving acetophenone and convenient aromatic aldehyde using ultrasonic agitation on basic alumina. The synthesized products were tested for their inhibitory effects on… Expand
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