Synthetic biology: lessons from the history of synthetic organic chemistry

@article{Yeh2007SyntheticBL,
  title={Synthetic biology: lessons from the history of synthetic organic chemistry},
  author={Brian J. Yeh and W. Lim},
  journal={Nature Chemical Biology},
  year={2007},
  volume={3},
  pages={521 - 525}
}
The mid-nineteenth century saw the development of a radical new direction in chemistry: instead of simply analyzing existing molecules, chemists began to synthesize them—including molecules that did not exist in nature. The combination of this new synthetic approach with more traditional analytical approaches revolutionized chemistry, leading to a deep understanding of the fundamental principles of chemical structure and reactivity and to the emergence of the modern pharmaceutical and chemical… Expand
83 Citations
Bottom-Up Synthetic Biology: Engineering in a Tinkerer’s World
  • 164
Directed evolution as a powerful synthetic biology tool.
  • 89
  • PDF
The Synthetic Nature of Biology
  • 18
Back to the future: Why we need enzymology to build a synthetic metabolism of the future
  • T. Erb
  • Biology, Medicine
  • Beilstein journal of organic chemistry
  • 2019
  • 11
  • PDF
Synthetic biology: putting synthesis into biology
  • J. Liang, Y. Luo, H. Zhao
  • Biology, Medicine
  • Wiley interdisciplinary reviews. Systems biology and medicine
  • 2011
  • 45
  • PDF
Synthetic biology toward medicinal natural products
  • 3
Designing synthetic biology.
  • C. Agapakis
  • Computer Science, Medicine
  • ACS synthetic biology
  • 2014
  • 43
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 48 REFERENCES
Synthetic biology: new engineering rules for an emerging discipline
  • 1,015
  • PDF
Metabolic engineering for drug discovery and development
  • 188
  • PDF
Synthetic gene circuits: design with directed evolution.
  • E. Haseltine, F. Arnold
  • Computer Science, Medicine
  • Annual review of biophysics and biomolecular structure
  • 2007
  • 123
  • PDF
Towards synthesis of a minimal cell
  • 372
  • PDF
The engineering of gene regulatory networks.
  • 212
  • PDF
A Short History of Chemistry
  • 15
Foundations for engineering biology
  • D. Endy
  • Biology, Environmental Science
  • Nature
  • 2005
  • 1,325
  • PDF
Genetic parts to program bacteria.
  • C. Voigt
  • Biology, Medicine
  • Current opinion in biotechnology
  • 2006
  • 241
  • PDF
The synthesis of ribonuclease A.
  • 223
  • PDF
...
1
2
3
4
5
...