Synthetic biology: Engineering Escherichia coli to see light

@article{Levskaya2005SyntheticBE,
  title={Synthetic biology: Engineering Escherichia coli to see light},
  author={Anselm Levskaya and Aaron Chevalier and Jeffrey J. Tabor and Zachary Booth Simpson and Laura A Lavery and Matthew Levy and Eric A. Davidson and Alexander D. Scouras and Andrew D. Ellington and Edward M. Marcotte and Christopher A. Voigt},
  journal={Nature},
  year={2005},
  volume={438},
  pages={441-442}
}
We have designed a bacterial system that is switched between different states by red light. The system consists of a synthetic sensor kinase that allows a lawn of bacteria to function as a biological film, such that the projection of a pattern of light on to the bacteria produces a high-definition (about 100 megapixels per square inch), two-dimensional chemical image. This spatial control of bacterial gene expression could be used to ‘print’ complex biological materials, for example, and to… 

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