Synthetic approaches to 2-tetralones

@article{Silveira2004SyntheticAT,
  title={Synthetic approaches to 2-tetralones},
  author={Claudio C. Silveira and Antonio Luiz Braga and Teodoro S. Kaufman and Eder Jo{\~a}o Lenard{\~a}o},
  journal={Tetrahedron},
  year={2004},
  volume={60},
  pages={8295-8328}
}

Figures and Tables from this paper

Asymmetric Reduction of Substituted 2‐Tetralones by Thermoanaerobacter pseudoethanolicus Secondary Alcohol Dehydrogenase

Ketones bearing two bulky substituents, named bulky–bulky ketones, were successfully reduced to their corresponding optically enriched alcohols by using various mutants of Thermoanaerobacter

An efficient route to highly enantioenriched tetrahydroazulenes and β-tetralones by desymmetrization reactions of δ,δ-diaryldiazoaceto-acetates.

A highly stereoselective desymmetrization reaction of δ,δ-diaryl-α-diazo-β-ketoesters catalyzed by chiral dirhodium carboxylates forms aromatic cycloaddition products in up to 97% ee.

A concise approach for the synthesis of 6-methoxy-2-tetralone

The commercially available 6-methoxy-1-tetralone 1 was converted [15] into the olefin 2 in 94% yield by heating under reflux with 2,4-pentanediol and a catalytic amount of p-toluenesulphonic acid

Bifunctional Brønsted Base Catalyst Enables Regio-, Diastereo-, and Enantioselective Cα -Alkylation of β-Tetralones and Related Aromatic-Ring-Fused Cycloalkanones.

TLDR
Under reaction conditions, not only enolization, and thus functionalization, occurs at the α-carbon atom of the β-tetralone exclusively, but adducts including all-carbon quaternary centers are also formed in highly diastereo- and enantioselective manner.

Asymmetric reduction of tetralones and their methoxy derivatives by Fusarium culmorum

Whole cells of the fungus Fusarium culmorum were used to carry out the bioreduction of 1- and 2-tetralones and their derivatives with a methoxy group in the aromatic ring. The process led to the

References

SHOWING 1-10 OF 277 REFERENCES

Quinazolines. VII. Synthesis of 1,3‐Diamino‐5,6‐dihydrobenzo[f]quinazolines

Eighteen new 1,3-diamino-5,6-dihydrobenzo[f] quinazolines (6, R. = alkyl, Cl, MeO) were synthesized via the condensation of appropriate 2-tetralones with cyanoguanidine under fusion conditions.

Versuche zur Synthese von Verbindungen der Steroidreihe

Reduction of the ketal II of 7-keto-1,4-dimethoxy-4b-methyl-5, 6, 7, 9, 10-hexahydrophenanthrene with lithium in liquid ammonia furnishes a corresponding dihydro derivative, from which a tricyclic

Einfache Darstellung von β-Tetralonen und β-Indanonen durch 1,2-Carbonylgruppenverschiebung

Simple Preparation of β-Tetralones and β-Indanones by a 1,2-Carbonyl Group Transposition By a four-step procedure, the ketones 3 are converted into the β-tetralones 7a-d and the β-indanones

The Synthesis of dl-a-Dihydrocaranone and ?-Lycorane

dl-α-Dihydrocaranone (XII) has been synthesized stereoselectively, using the ring-closure reaction via benzyne intermediate of N-(2-bromo-4,5-methylenedioxybenzyl)octahydroindole-6-one (X) with

A Total Synthesis of the Racemic Sesquiterpene Parvifoline

A total synthesis of the sesquiterpene (±)-parvifoline 1 from the symmetrical naphthalene 4 is reported. The key step of the synthesis was a Stork−Landesman two-carbon ring expansion of β-tetralone

Bridged ring systems. Part XVI. A synthetic approach to lycopodium alkaloids

A novel ring annelation technique has been devised to convert 9-oxobicyclo[3,3,1]non-3-ene-1-carboxylic acid (3; R = CO2H) intoN-acetyl-2-azatricyclo[5,3,3,01,6]tridecane (2; R = Ac), which comprises

A New, Simple Procedure for the Preparation of 8-Methoxy-2-Tetralone

Abstract 8-Methoxy-2-tetralone (6) can be easily prepared in approximately 50% overall yield starting from 2-bromophenylacetic acid (1), utilizing a Friedel-Crafts acylation/cyclization, ketone
...