Synthetic approach to the generation of antibody diversity

@inproceedings{Shim2015SyntheticAT,
  title={Synthetic approach to the generation of antibody diversity},
  author={Hyunbo Shim},
  booktitle={BMB reports},
  year={2015}
}
The in vitro antibody discovery technologies revolutionized the generation of target-specific antibodies that traditionally relied on the humoral response of immunized animals. An antibody library, a large collection of diverse, pre-constructed antibodies, can be rapidly screened using in vitro display technologies such as phage display. One of the keys to successful in vitro antibody discovery is the quality of the library diversity. Antibody diversity can be obtained either from natural B… CONTINUE READING

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