Synthetic approach to gain insight into antigenic determinants of cephalosporins: in vitro studies of chemical structure-IgE molecular recognition relationships.

@article{Montannez2011SyntheticAT,
  title={Synthetic approach to gain insight into antigenic determinants of cephalosporins: in vitro studies of chemical structure-IgE molecular recognition relationships.},
  author={Maria Isabel Montannez and Cristobalina Mayorga and Mar{\'i}a Jos{\'e} Alvarez Torres and Adriana Alexandra Aparicio Ariza and Miguel Blanca and Ezequiel Perez-Inestrosa},
  journal={Chemical research in toxicology},
  year={2011},
  volume={24 5},
  pages={706-17}
}
Cephalosporins, after penicillins, are the most widely used antibacterial agents in infectious diseases and the cause of adverse immune reactions in the world. Whether a patient with a suspected allergy to a β-lactam can safely take a cephalosporin is often a matter of debate. However, there are no tests with enough sensitivity to detect allergy to… CONTINUE READING