Synthetic analogues relevant to the structure and function of zinc enzymes.

@article{Parkin2004SyntheticAR,
  title={Synthetic analogues relevant to the structure and function of zinc enzymes.},
  author={Gerard Parkin},
  journal={Chemical reviews},
  year={2004},
  volume={104 2},
  pages={
          699-767
        }
}
  • G. Parkin
  • Published 24 January 2004
  • Chemistry, Medicine
  • Chemical reviews
Variable-temperature X-ray diffraction study of structural parameters of NH---S hydrogen bonds in triethylammonium and pyridinium silanethiolates.
TLDR
All results point to the higher energy of bonding in TDST-TEA both in the solid state and in solution, indicating good stabilization of the system for a wide range of D-H...A distances. Expand
A Hydroxyl-bridged Dinuclear Copper Complex Having Planar Structure Shows Efficient DNA Cleavage Activity in Aqueous Solution
A new dinuclear copper(II) complex, [Cu(DPA)OH]2⋅2ClO4(Cu2-DPA2, DPA = di(pyridin-2-yl)amine), was synthesized and structurally characterized. The complex crystallized in a triclinic P-1 space group,Expand
A LADH-like Zn-MOF as an efficient bifunctional catalyst for cyanosilylation of aldehydes and photocatalytic oxidative carbon–carbon coupling reaction
  • Feng Li, Ren Ma, +4 authors Shengli Gao
  • Chemistry
  • 2021
Abstract The rational design of component and coordination configuration of active center is critical and useful to the development of multifunctional MOF-based catalysts. Herein, a bifunctionalExpand
A New Dimeric Copper(II) Complex of Hexyl Bis(pyrazolyl)acetate Ligand as an Efficient Catalyst for Allylic Oxidations
TLDR
The present study highlights the potential of copper(II) complexes containing functionalized bis(pyrazol-1-yl)acetate ligands as efficient catalysts for allylic oxidations and shows relevant improvements with respect to classical Kharasch–Sosnovsky reactions in terms of rate and amount of reagents. Expand
A combined experimental and theoretical rationalization of an unusual zinc(ii)-mediated conversion of 18-membered Schiff-base macrocycles to 18-membered imine–amine macrocycles with imidazolidine side rings: an investigation of their bio-relevant catalytic activities
The 2 : 2 condensation reaction of 2,6-diformyl-4-isopropyl phenol and N′-(2-aminoethyl)ethane-1,2-diamine leads to a macrocycle Schiff base ligand (H2L) with the N6O2 chromophore, which in theExpand
A de novo binuclear zinc enzyme with DNA cleavage activity
TLDR
Results indicate that the DFsc scaffold is a good model system to carry out careful structure–function relationship studies to understand key structural features that influence reactivity in natural binuclear zinc hydrolases, as it is the first report of a binuclear model system in a protein scaffold. Expand
Aromaticity in catalysis: metal ligand cooperation via ligand dearomatization and rearomatization.
TLDR
Representation of ligand systems will be highlighted and a comparison between the Milstein and the Huang pincer system will be discussed to provide theoretical and conceptual insights. Expand
BioMetAll: Identifying Metal-Binding Sites in Proteins from Backbone Preorganization
TLDR
This study shows that BioMetAll offers a versatile platform for numerous fields of research at the interface between inorganic chemistry and biology and allows to highlight the role of the preorganization of the protein backbone as a marker for metal binding. Expand
Bioinorganic insights of the PQQ-dependent alcohol dehydrogenases.
TLDR
The three types of PQQ-dependent ADHs are reviewed with special focus on their structural features and electron transfer processes, and an additional [2Fe-2S] cluster has been discovered recently. Expand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 10 REFERENCES
For examples of other studies of the coordination chemistry of zinc with amino acids, small peptides, ligands that incorporate amino acid residues and carbohydrate derivatives, see
  • 2002
Scorpionates: The Coordination Chemistry of Polypyrazolylborate Ligands
This work deals with polypyrazolylborates (scorpionates), a class of ligands known since 1966, which have become increasingly popular with inorganic, organometallic and co-ordination chemists sinceExpand
Zinc Metalloproteases Health Dis
  • Dermatol. Res
  • 1999
Advances in Chemical Conversions For Mitigating Carbon Dioxide; Elsevier
  • New York,
  • 1998
Comments Inorg
  • Chem. 1995,
  • 1995
Zinc in Human Biology
TLDR
The Biological Significance of Zinc for Man: Problems and Prospects and putative Therapeutic Roles for Zinc are described. Expand
Matrix Metalloproteinases Inhib
  • Adv. Enzymol. Relat. Areas Mol. Biol
  • 1984
For studies pertaining to this interconversion in carbonic anhydrase and metal-substituted derivatives, see
  • Inorg. Chem. 1982,
  • 1981
Lange's Handbook of Chemistry
  • J. Dean
  • Chemistry, Computer Science
  • 1978
TLDR
This encyclopedic work includes authoritative coverage of atomic and molecular structure, organic chemistry (revised), inorganic, analytical, and electro- chemistry, mathematics as applied to chemistry, and more. Expand