Synthetic GPI as a candidate anti-toxic vaccine in a model of malaria

Abstract

The malaria parasite Plasmodium falciparum infects 5–10% of the world's population and kills two million people annually. Fatalities are thought to result in part from pathological reactions initiated by a malarial toxin. Glycosylphosphatidylinositol (GPI) originating from the parasite has the properties predicted of a toxin; however, a requirement for… (More)
DOI: 10.1038/nature00937

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