Synthetic DNA delivery systems

@article{Luo2000SyntheticDD,
  title={Synthetic DNA delivery systems},
  author={Dan Luo and W. Mark Saltzman},
  journal={Nature Biotechnology},
  year={2000},
  volume={18},
  pages={33-37}
}
The ability to safely and efficiently transfer foreign DNA into cells is a fundamental goal in biotechnology. Toward this end, rapid advances have recently been made in our understanding of mechanisms for DNA stability and transport within cells. Current synthetic DNA delivery systems are versatile and safe, but substantially less efficient than viruses. Indeed, most current systems address only one of the obstacles to DNA delivery by enhancing DNA uptake. In fact, the effectiveness of gene… Expand

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