Synthesizing and tuning stochastic chemical reaction networks with specified behaviours

@inproceedings{Murphy2018SynthesizingAT,
  title={Synthesizing and tuning stochastic chemical reaction networks with specified behaviours},
  author={Niall Murphy and Rasmus M. Petersen and Andrew Phillips and Boyan Yordanov and Neil Dalchau},
  booktitle={Journal of the Royal Society, Interface},
  year={2018}
}
Methods from stochastic dynamical systems theory have been instrumental in understanding the behaviours of chemical reaction networks (CRNs) arising in natural systems. However, considerably less attention has been given to the inverse problem of synthesizing CRNs with a specified behaviour, which is important for the forward engineering of biological systems. Here, we present a method for generating discrete-state stochastic CRNs from functional specifications, which combines synthesis of… CONTINUE READING
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Programmability of Chemical Reaction Networks

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Synthesizing and tuning stochastic chemical reaction networks with specified behaviours

N Murphy, R Petersen, A Phillips, B Yordanov, N Dalchau
  • Dryad Digital Repository
  • 2018