Synthesizing Stochasticity in Biochemical Systems

  title={Synthesizing Stochasticity in Biochemical Systems},
  author={Brian Fett and Jehoshua Bruck and Marc D. Riedel},
  journal={2007 44th ACM/IEEE Design Automation Conference},
Randomness is inherent to biochemistry: at each instant, the sequence of reactions that fires is a matter of chance. Some biological systems exploit such randomness, choosing between different outcomes stochastically - in effect, hedging their bets with a portfolio of responses for different environmental conditions. In this paper, we discuss techniques for synthesizing such stochastic behavior in engineered biochemical systems. We propose a general method for designing a set of biochemical… CONTINUE READING
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