Synthesis of three triterpene series and their activity against respiratory syncytial virus

  title={Synthesis of three triterpene series and their activity against respiratory syncytial virus},
  author={Gloria N Santos da Silva and Diana Monti Atik and Jheini L Antunes Fernandes and Deise de Freitas do Nascimento and Tiago Fazolo and Ana Paula Duarte de Souza and Simone Cristina Baggio Gnoatto},
  journal={Archiv der Pharmazie},
The human respiratory syncytial virus (hRSV) is a leading cause of hospitalization due to acute lower respiratory infection especially in infants and young children, sometimes causing fatal cases. The monoclonal antibody palivizumab is one of the available options for preventing this virus, and at the moment there are several hRSV vaccine trials underway. Unfortunately, the only drug option to treat hRSV infection is ribavirin, which can be used in severe high‐risk cases. For this reason, new… Expand
2 Citations
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