Synthesis of thermo-sensitive CS-g-PNIPAM/CMC complex nanoparticles for controlled release of 5-FU.

Abstract

In this paper, self-assembled thermo-sensitive polyelectrolyte complex nanoparticles formed from chitosan-graft-poly(N-isopropylacrylamide)/carboxymethyl cellulose (CS-g-PNIPAM/CMC) were prepared for entrapment and release of 5-fluorouracil (5-FU). The morphology and size of the nanoparticles were observed by transmission electron microscopy (TEM) and… (More)
DOI: 10.1016/j.ijbiomac.2012.08.033

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