Synthesis of the kappa-agonist CJ-15,161 via a palladium-catalyzed cross-coupling reaction.

  title={Synthesis of the kappa-agonist CJ-15,161 via a palladium-catalyzed cross-coupling reaction.},
  author={Arun K. Ghosh and Janice E. Sieser and St{\'e}phane Caron and Timothy J. N. Watson},
  journal={Chemical communications},
Syntheses of CJ-15,161 (1) involving intermolecular N-arylation of an appropriately functionalized diamine, obtained from the precursor alpha-amino acids or, more conveniently, from the corresponding 1,2-amino alcohols via 1,2,3-oxathiazolidine-2,2-dioxide 22, are reported. 
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