Synthesis of the bicyclic core of the nucleoside antibiotic octosyl acid A.

  title={Synthesis of the bicyclic core of the nucleoside antibiotic octosyl acid A.},
  author={Jesse D. More and Nathaniel S. Finney},
  journal={The Journal of organic chemistry},
  volume={71 6},
The bicyclic core of octosyl acid A has been prepared using a diastereoselective acetylide addition and 6-endo selenoetherification as key steps. A detailed study of the selenoetherification reaction and difficulties encountered in the conversion of a phenyl group to a carboxylic acid will be discussed. 
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