Synthesis of subgenomic RNAs by positive-strand RNA viruses.

@article{Miller2000SynthesisOS,
  title={Synthesis of subgenomic RNAs by positive-strand RNA viruses.},
  author={W. Allen Miller and Gennadiy Koev},
  journal={Virology},
  year={2000},
  volume={273 1},
  pages={
          1-8
        }
}
f b w t ( t g s p t n p Many RNA viruses encode more than one gene on a single genomic RNA. Yet only the first gene, or open reading frame (ORF), on a normal eukaryotic mRNA is translated. Thus, downstream genes on viral genomes are expressed either via novel translational events or, more commonly, by deployment of subgenomic mRNAs (sgRNAs). Subgenomic RNAs of positive-strand viruses have the same 39 ends as genomic RNA, but have deleions at the 59 ends to bring the 59 end of the RNA in… 

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