Synthesis of structured phospholipids by immobilized phospholipase A2 catalyzed acidolysis.

@article{Vikbjerg2007SynthesisOS,
  title={Synthesis of structured phospholipids by immobilized phospholipase A2 catalyzed acidolysis.},
  author={Anders Falk Vikbjerg and Huiling Mu and Xuebing Xu},
  journal={Journal of biotechnology},
  year={2007},
  volume={128 3},
  pages={545-54}
}
Acyl modification of the sn-2 position in phospholipids (PLs) was conducted by acidolysis reaction using immobilized phospholipase A(2) (PLA(2)) as the catalyst. In the first stage we screened different carriers for their ability to immobilize PLA(2). Several carriers were able to fix the enzyme and maintain catalytic activity; however, the final choice of carrier for the continued work was a non-ionic weakly polar macroreticular resin. Response surface methodology was applied to evaluate the… CONTINUE READING