Synthesis of quinazolines via CuO nanoparticles catalyzed aerobic oxidative coupling of aromatic alcohols and amidines.

Abstract

CuO nanoparticles were found to be efficient catalysts for the synthesis of quinazoline derivatives; twenty-four products were obtained with good to excellent yields via reaction of N-arylamidines and aromatic aldehydes or benzyl alcohol in air. Neither a base nor an organic oxidant was necessary, and CuO nanoparticles can be recycled without a significant decrease in catalytic activity.

DOI: 10.1039/c4ob00569d

Cite this paper

@article{Zhang2014SynthesisOQ, title={Synthesis of quinazolines via CuO nanoparticles catalyzed aerobic oxidative coupling of aromatic alcohols and amidines.}, author={Wu Zhang and Fei Guo and Fei Wang and Na Zhao and Liang Liu and Jia Li and Zhenghua Wang}, journal={Organic & biomolecular chemistry}, year={2014}, volume={12 30}, pages={5752-6} }