Corpus ID: 92625881

Synthesis of phosphonates and organofluorine compounds for bio-organic studies

@inproceedings{Knight1999SynthesisOP,
  title={Synthesis of phosphonates and organofluorine compounds for bio-organic studies},
  author={Lee Knight},
  year={1999}
}
This thesis focuses on two main areas: the synthesis of novel anti-metabolites of 1-deoxy- D-xyulose-5-phosphate (DXP) and the stereoelectronics which influence the conformation of fluoromethyl groups in organic compounds. DXP, a sugar phosphate, has recently been established as a key biosynthetic intermediate to a number of plant and bacterial co-enzymes and vitamins. Chapter 1 describes the role of DXP in three biosynthetic pathways; in the formation of the isoprenoid building block… Expand

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TLDR
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