Synthesis of peptides and pyrazines from β-amino alcohols through extrusion of H2 catalyzed by ruthenium pincer complexes: ligand-controlled selectivity.

@article{Gnanaprakasam2011SynthesisOP,
  title={Synthesis of peptides and pyrazines from $\beta$-amino alcohols through extrusion of H2 catalyzed by ruthenium pincer complexes: ligand-controlled selectivity.},
  author={Boopathy Gnanaprakasam and Ekambaram Balaraman and Yehoshoa Ben‐David and David Milstein},
  journal={Angewandte Chemie},
  year={2011},
  volume={50 51},
  pages={
          12240-4
        }
}
Peptides constitute one of the most important families of compounds in chemistry and biology. Short peptides have found intriguing biological and synthetic applications. For example, the conformational rigidity of cyclic peptides makes them attractive for drug discovery and biomedical research. Several cyclic peptides that show intriguing biological activity are found in nature. Cyclic peptides have been discovered that are novel antibiotics, enzyme inhibitors, and receptor antagonists. Among… 

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