Synthesis of nucleoside analogs and new Tat protein inhibitors

A. Ane; G. Prestat; G. T. Manh; M. Thiam; S. Josse; M. Pipelier; J. Lebreton; J. Pradère; D. Dubreuil

DOI:10.1351/pac200173071189

Corpus ID: 8109943

Synthesis of nucleoside analogs and new Tat protein inhibitors

@article{Ane2001SynthesisON,
  title={Synthesis of nucleoside analogs and new Tat protein inhibitors},
  author={A. Ane and G. Prestat and G. T. Manh and M. Thiam and S. Josse and M. Pipelier and J. Lebreton and J. Prad{\`e}re and D. Dubreuil},
  journal={Pure and Applied Chemistry},
  year={2001},
  volume={73},
  pages={1189 - 1196}
}

A. Ane, G. Prestat, +6 authors D. Dubreuil

Published 2001

Chemistry

Pure and Applied Chemistry

Two studies, concerning the synthesis of original nucleoside analogs regarded as an application of heterochemistry on thiaazaheterocycle systems from thiaazabutadienes are discussed. The preparation of new N- and C-nucleosides is presented. In the second part, the discovery of aromatic polycyclic derivatives as inhibitors of Tat protein is exposed. The work presented takes into account the participation of African partners in further synthetic research programs carried out in collaboration with… CONTINUE READING

View via Publisher