Synthesis of novel hybrid molecules from precursors with known antiparasitic activity.

@article{Saadeh2009SynthesisON,
  title={Synthesis of novel hybrid molecules from precursors with known antiparasitic activity.},
  author={Haythem A. Saadeh and Ibrahim M. Mosleh and Mohammad S. Mubarak},
  journal={Molecules},
  year={2009},
  volume={14 4},
  pages={1483-94}
}
Three novel new compounds derived from antiparasitic precursors have been synthesized and tested for their antiamoebic and antigiardial activities. The condensation of 2-(2-methyl-5-1H-nitroimidazolyl)ethylamine (6) with 5-nitro-2-furylacrylic acid (7) gave 3-(5-nitrofuran-2-yl)-N-[2-(5-nitroimidazol-1-yl)ethyl]acrylamide (8). Condensation of 7 with 7… CONTINUE READING