Synthesis of novel 1-pyrazolylpyridin-2-ones as potential anti-inflammatory and analgesic agents.

Abstract

A new series of 4-alkyl/aryl-2-oxo-1-pyrazolyl-1,2-dihydropyridine-3-carbonitriles, pyrazolo[3,4-b]pyridine-5-carbonitriles and pyrido[2,3-d]pyrimidine-6-carbonitriles have been synthesized and tested for their anti-inflammatory and analgesic activities. Among the tested compounds, 3e and 8b exhibited comparable anti-inflammatory activity to the standard… (More)

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Cite this paper

@article{Ismail2007SynthesisON, title={Synthesis of novel 1-pyrazolylpyridin-2-ones as potential anti-inflammatory and analgesic agents.}, author={Magda Ismail and Yousry Ahmed Ammar and Heba S A El-Zahaby and Sally I Eisa and Saber El-Sayed Barakat}, journal={Archiv der Pharmazie}, year={2007}, volume={340 9}, pages={476-82} }